翻訳と辞書 Words near each other ・ Nerve center ・ Nerve centre ・ Nerve Centre (organisation) ・ Nerve compression syndrome ・ Nerve conduction study ・ Nerve conduction velocity ・ Nerve cord ・ Nerve Damage ・ Nerve Engine ・ Nerve fascicle ・ Nerve fiber ・ Nerve fiber layer ・ Nerve Filter ・ Nerve growth factor ・ Nerve growth factor IB ・ Nerve growth factor receptor ・ Nerve guidance conduit ・ Nerve induction ・ Nerve injury ・ Nerve Net ・ Nerve net ・ Nerve of a covering ・ Nerve of Latarjet ・ Nerve of pterygoid canal ・ Nerve of Wrisberg ・ Nerve plexus ・ Nerve point of neck ・ Nerve root ・ Nerve sheath tumor ・ Nerve Software Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Nerve growth factor receptor ： ウィキペディア英語版 Nerve growth factor receptor Nerve growth factor receptors are a group of growth factor receptors which specifically bind to neurotrophins. There are two classes of receptors, p75 and the "Trk" family of Tyrosine kinases receptors. * p75 is a low affinity neurotrophin receptor, to which all neurotrophins bind. It is a member of the tumour necrosis super family. In some contexts, the phrase "x" only applies to this receptor. * The Trk family include TrkA, TrkB, and TrkC, and will only bind with specific neurotrophins, but with a much higher affinity. The Trks mediate the functional signals of the neurotrophins. * NGF binds to TrkA, BDNF and NT-4 bind to TrkB and NT-3 binds to TrkC. In addition NT-3 also binds to and activates TrkA and TrkB but it does so less efficiently. * Whilst the Trk receptors have a clearly defined trophic role, p75 receptors activate signalling pathways which can also result in apoptosis. ==TrkA, B, and C receptors== TrkA is a nuclear receptor (meaning it mediates its actions by causing the addition of phosphate molecules on certain tyrosines in the cell, activating cellular signaling). There are other related Trk receptors (TrkB and TrkC), and there are other neurotrophic factors structurally related to NGF (BDNF, NT-3, and NT-4) * TrkA mediates the effects of NGF * TrkB binds and is activated by BDNF, NT-4, and NT-3 * TrkC binds and is activated only by NT-3 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Nerve growth factor receptor」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.